The Tobacco Reference Guide by David Moyer

The Tobacco Reference Guide

by David Moyer, MD.

Chapter 8 Other Cancers

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Other Cancers: Esophageal, stomach, and small intestinal

cancers

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Of the 10,200 deaths from cancer of the esophagus in 1993, about 80 percent were

attributable to cigarette smoking.

NEJM, March 31, 1994, p. 909

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The combination of smoking and drinking can boost the risk of esophageal cancer by

more than 100 times.

Reuters, August 9, 1999

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Smoking is a major risk factor for esophageal and gastric cardia (stomach)

adenocarcinomas, accounting for about 40% of all cases. The risk of these cancers

was increased 2.4-fold in current cigarette smokers, with little reduction in risk

observed until 30 years after smoking cessation. The risk rose with increasing

intensity and duration of smoking. The risks for developing squamous cell carcinoma

of the esophagus were estimated to be more than five times higher among current

smokers, 2.8 times higher among ex-smokers, and more than three times higher

among liquor drinkers. The lag between smoking onset and the development of these

cancers is extremely long; it may exceed 30 years.

Journal of the National Cancer Institute, September 3, 1997, pp. 1248 and 1277-84

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Male smokers in China have a 3.6-fold increased risk for esophageal cancer, and a

2-fold increase in liver cancer, the latter independent of alcohol consumption.

JAMA, November 12, 1997, p. 1501

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In a study from the University of Southern California reported in the International

Journal of Cancer, smoking tripled the risk of small intestinal cancer in men.

Reuters Medical News, March 7, 1997

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